Mayo Clinic

Histology Technician or Histotechnologist (HT/HTL) - Neurology

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Mayo Clinic is seeking Histology Technicians and Histotechnologists (HT/HTL) to join a dynamic and collaborative team within Neurology.

The Neurology Laboratories at Mayo Clinic process a high volume of peripheral nerve specimens. Our laboratories take pride in contributing to accurate patient diagnoses and advancing scientific knowledge through collaboration with pathologists, clinicians, and research investigators.

As an HT/HTL, you will play a critical role in preparing high-quality slides for pathologist review. Responsibilities may include embedding, microtomy, cryotomy, special staining, immunohistochemical techniques, and handling of fresh and complex specimens. The work requires attention to detail, adaptability, and a commitment to quality and patient care.

In addition, you will:

  • Support training and onboarding of students and new employees
  • Collaborate across multidisciplinary teams to ensure timely and accurate results
  • Contribute to a respectful, inclusive, and team-oriented work environment
  • Adapt to the unique demands and workflows of different subspecialty laboratories

Mayo Clinic offers extensive opportunities for professional growth and career advancement . Whether you are interested in developing technical expertise across multiple lab areas or specializing in a particular discipline, this role provides a strong foundation for long-term career development.

Don’t miss the opportunity to be part of a team dedicated to excellence in patient care, innovation, and laboratory medicine.

Histology Technician / Histotechnologist (HT/HTL)

As a Histology Technician or Histotechnologist, you will perform a variety of technical procedures to prepare high-quality microscopic slide preparations used by pathologists for diagnostic and prognostic evaluation.

These procedures may include:

  • Specimen accessioning and identification
  • Specimen processing and embedding
  • Microtomy techniques, including:
    • Paraffin
    • Frozen (cryotomy)
    • Plastic sections
  • Routine Hematoxylin and Eosin (H&E) staining
  • Special stains
  • Immunofluorescence
  • Immunohistochemical (IHC) staining
  • In situ hybridization

This vacancy is not eligible for sponsorship, and we will not sponsor or transfer visas for this position.

Histology Technician (HT):

  • Associate degree required.
  • Coursework including 24 semester hours of the following:
    • A minimum of 12 credit hours in chemistry, biology, or medical laboratory technology
    • 6 credit hours in chemistry
    • 6 credit hours in biology
  • Histology Technician (HT) certified by the American Society of Clinical Pathologists (ASCP) required by start date

Histotechnologist (HTL):

  • Bachelor’s degree required.
  • Histotechnologist (HTL) certified by the American Society of Clinical Pathologists (ASCP) required by start date

Additional Qualifications

  • Graduate of a NAACLS accredited program preferred.
  • Graduates of the Mayo Clinic School of Health Sciences Histology Technician Program will receive preference.
  • Ability to accommodate scheduling adjustments, off shifts, holidays, on-call, and weekend work assignments.

*Employees obtaining certification(s) after January 1, 2004, will be required to demonstrate evidence of ongoing maintenance of certification.