Regional Digital Project and Change Manager

Location: Macclesfield, UK

At AstraZeneca, science compels us to push the boundaries of what is possible to turn science into life-changing medicines for patients who need them most. We deliver breakthrough science by creating thriving, vibrant and open science centres where our scientists are free to pursue their ideas and collaborate both with colleagues and our academic and industry partners.

Introduction to role:
Are you ready to turn digital strategy into measurable results across a complex regional supply network? In this role, you will convert vision into delivery, shaping the solutions that help our medicines reach patients faster and more reliably.

You will work at the heart of our regional digital transformation, collaborating with leaders and teams across the UK (Macclesfield), France (Dunkerque) and Egypt (Cairo). Partnering closely with IT and business stakeholders, you will identify high-value opportunities, deliver PoCs and pilots, and scale proven solutions that create competitive advantage. How will you move from a promising idea to a scaled outcome that improves flow, quality and cost?

Accountabilities:

Opportunity Shaping: Partner with local stakeholders and IT to ensure business opportunities are fully understood and customer requirements clearly mapped into actionable use cases.
Value Case and Benefits: Evaluate and document the business benefits of proposed solutions, and drive benefits management and realisation through to measurable outcomes.
Fit-for-Purpose Technology: Safeguard the relevance of proposed technologies to the problem, ensuring standardised platforms and processes are selected and adopted.
Delivery Excellence: Ensure On Time, In Full delivery of digital projects, coordinating process and people to land change effectively and sustainably.
Governance and Risk Management: Oversee and proactively manage project actions, risks and reporting; influence priorities and resource commitments across sites.
Strategy Alignment: Support product and functional teams in their digitalisation strategies, aligning initiatives to regional plans and long-term goals.
Scale and Knowledge Transfer: Lead PoCs and pilots to successful scale-up; promote learning and knowledge transfer across sites and maintain oversight of local and global digitalisation initiatives.
Regional Representation and Inclusion: Represent users across the UK, Dunkerque and Cairo sites with strong inclusion and cultural sensitivity, ensuring solutions work in each context while remaining scalable.

Essential Skills/Experience:

Proven experience of successfully deploying a variety of business analysis tools/techniques to enable business change
Strong engagement, communication and stakeholder management skills, including excellent presentation and influencing skills
Experience of virtual collaboration to lead, shape and develop innovative solutions
Practical usage of Agile Methodology
Cross industry business awareness/business domain knowledge
Broad understanding of pharmaceutical manufacturing processes
Expert in Lean methodologies including process mapping, problem solving and continuous improvement
Project Management Skills
Challenge, negotiation and influence
Stakeholder Management both internal and external
Benefits Management and Realisation
Competent with Lean methodology
GMP knowledge
Manufacturing knowledge
Presentation, Communication & Facilitation
Customer Focus
Networking
Compliance
Business Process Management

Desirable Skills/Experience:

Experience leading large/complex change projects in matrixed environments
Experience of working in a regulated environment
Degree in relevant discipline or formal certification in Project or Change Management
Experience of working in a global organisation with complex/geographical context
User Centred Design (User Experience, User Interface Design and Business Process Design)

Why AstraZeneca:

Join a team that turns cutting-edge ideas into real-world impact for patients. Here, unexpected teams gather around the same problem to unleash bold thinking, blending digital and Lean practices with modern science and manufacturing to keep pace with constant new products and launches.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

You will thrive in a supportive, high-energy environment that values kindness alongside ambition, where speaking up, learning fast and acting with purpose are part of everyday work. Your leadership will help shape a resilient, forward-looking supply network that continuously improves how medicines are made and delivered, creating tangible value at scale.

If you are ready to lead regional digital change that accelerates how life-changing medicines reach patients, take the next step and apply to shape what comes next!

Date Posted

19-Jun-2026

Closing Date

02-Jul-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.