pfizer

Sr. Manager Investigations and Operations Governance

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USE YOUR POWER FOR PURPOSE

Our breakthroughs would not reach the hands of patients without our dedicated pharmaceutical manufacturing team. We rely on agile members who understand the critical impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and continuously strive to improve outcomes. Your efforts ensure that patients and physicians have timely access to the medicines they need.

WHAT YOU WILL ACHIEVE

In this role, you will:

  • Lead Investigations and CAPA Excellence.

  • Own and govern the Operations investigations and CAPA team.

  • Establish a proactive investigation culture focused on root cause rigor and reduction of repeat events.

  • Oversee performance of investigation teams.

  • Establish and Lead Operations Governance.

  • Develop and sustain governance frameworks including KPI review forums and escalation pathways.

  • Define and monitor key performance indicators.

  • Align priorities across Investigations, CI, and site operations.

  • Help improve adherence to IMEx principles and ways of working throughout Operations.

Drive Continuous Improvement and Operational Excellence

  • Define and deploy the CI strategy in partnership with the Operations Senior Managers.

  • Lead teams executing CI initiatives delivering measurable improvements.

  • Embed Lean, TPM, and Six Sigma methodologies.

Enable Data-Driven Decision Making

  • Oversee data analytics and trend identification.

  • Ensure consistent use of structured problem-solving methods.

  • Translate data into actionable insights.

Build Organizational Capability

  • Lead, develop, and coach teams.

  • Build capability in investigation excellence and CI methodologies.

  • Champion a culture of accountability and continuous improvement.

Ensure Compliance

  • Ensure alignment with GWI, cGMP, and regulatory requirements.

  • Maintain inspection readiness.

HERE IS WHAT YOU NEED (Minimum Requirements)

  • Applicant must have a bachelor's degree with at least 6 years of experience; OR a master's degree with at least 5 years of experience; OR a PhD with 1+ years of experience.

  • Excellent verbal, written, and presentation skills

  • Proven ability to manage complex projects and lead cross-functional teams

  • In-depth knowledge of pharmaceutical manufacturing processes and cGMP requirements

  • Strong analytical and problem-solving skills

BONUS POINTS IF YOU HAVE (Preferred Requirements)

  • Previous experience leading investigations and continuous improvement initiatives.

  • Experience in GMP-regulated environments.

  • Strong problem-solving and communication skills.

  • Strong financial acumen and experience managing budgets.

  • Strong leadership skills with the ability to influence senior management decisions.

  • Experience in knowledge management and sharing practices.

  • Ability to assess and develop talent within the organization.

  • Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use.


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

OTHER JOB DETAILS

Work Location Assignment: On site

Relocation support available

Last Date to Apply for Job: July 9, 2026


The annual base salary for this position ranges from $139,100.00 to $231,900.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.





Relocation assistance may be available based on business needs and/or eligibility.




Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.




Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.




EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.




To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.


Manufacturing